HPLC is a potent analytical tool, allowing for the separation, identification and quantification of drug substances. It also presents many challenges, from the correct use of instrumentation, to analysing results, to the fulfilment of the regulatory requirements of method validation.
Over two days, this course will offer delegates the opportunity to examine the core aspects of HPLC theory and method development, including troubleshooting. Over the course of an optional third day, delegates will examine quantitation and method validation.
Delegates may choose to attend either the first 2 or all 3 days.
The course is also available as online course, check the website for dates>>
Dr Mark Powell is a Fellow of the Royal Society of Chemistry (RSC) with over 25 years’ experience as an analytical chemist. He is an expert in sampling and sample preparation, chromatography (liquid and gas), spectroscopy (atomic and molecular) and pharmaceutical dissolution testing. Mark was Programme Leader for the MSc in Instrumental Chemical Analysis at Liverpool John Moores University’s School of Pharmacy and Chemistry. In 2010 Mark was appointed Scientific Manager at Quay Pharmaceuticals, his work there resulting in a number of published papers and presentations at international scientific conferences. Mark left Quay Pharmaceuticals in September 2013 to set up Mark Powell Scientific, working in training, consultancy and expert witness assignments.
Know the important chemical parameters affecting HPLC separation
Be familiar with chromatographic theory
Understand HPLC retention mechanisms and stationary phase types
Know how to improve resolution between closely-eluting peaks
Be able to troubleshoot HPLC system faults
Approach the development and validation of quantitative HPLC methods in a logical, scientifically-sound manner
This course will be beneficial to personnel working in the following areas:
Very interactive course and it was oriented for our specific needs for improvement!
Really enjoyed the ability to interact and discuss with the trainer the problems and issues I am facing everyday and queries about analytical challenges.
The course covers a range of levels to keep each course member on the same level of understanding. I enjoyed discussion options for improvements that can be applied. Especially enjoyed the troubleshooting and validation sections!